Preclinical Services
Preclinical research services including toxicology, PK/ADME, efficacy studies, safety pharmacology, and animal model development.
Carcinogenicity Studies
Long-term rodent bioassays and alternative carcinogenicity models (Tg.rasH2, p53+/-).
2 CROs
Efficacy Studies
In vivo pharmacology and disease model studies to evaluate therapeutic efficacy of drug candidates.
7 CROs
General Toxicology
Single-dose and repeat-dose toxicity studies in rodent and non-rodent species per ICH guidelines.
14 CROs
Genetic Toxicology
Ames test, in vitro chromosomal aberration, in vivo micronucleus, and other mutagenicity assessments.
5 CROs
PK/ADME Studies
Pharmacokinetic and ADME studies including absorption, distribution, metabolism, and excretion profiling.
13 CROs
Reproductive Toxicology
Fertility, embryo-fetal development, and pre/postnatal development studies per ICH S5 guidelines.
3 CROs
Safety Pharmacology
Core battery and supplemental safety pharmacology studies assessing cardiovascular, respiratory, and CNS effects.
10 CROs