Hit-to-Lead Optimization CROs
Systematic refinement of initial screening hits into viable lead compounds through medicinal chemistry and SAR analysis.
4 organizations offer this service
WuXi AppTec
FeaturedLeading global pharmaceutical and medical device open-access capability and technology platform. WuXi AppTec provides services spanning from discovery through manufacturing across small molecules, biologics, and cell/gene therapies.
Pharmaron
Integrated pharmaceutical R&D service platform offering drug discovery, preclinical, clinical, and commercial manufacturing services to biotech and pharma companies globally.
Evotec
Drug discovery and development company offering a range of discovery and preclinical services including target validation, hit identification, lead optimization, and ADME/PK.
Reaction Biology
Specialty CRO providing biochemical and cell-based assay services for drug discovery. Known for kinase profiling, epigenetic screening, and custom assay development.